INT186147

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Camk4, Creb1) mitochondrion (Creb1) DNA binding (Creb1)
cytoplasm (Camk4) signal transduction (Camk4) nucleocytoplasmic transport (Camk4)
Camk4 (Mus musculus)
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 4 75.44 Quite High
analgesia 15 32.16 Quite Low
antidepressant 2 23.76 Low Low
tail-flick 4 5.00 Very Low Very Low Very Low
amygdala 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 58 100.00 Very High Very High Very High
Targeted Disruption 3 94.28 High High
Disease 1 76.64 Quite High
Schizophrenia 1 75.28 Quite High
Cancer 1 72.80 Quite High
Stress 34 56.88 Quite High
Post-traumatic Stress Disorder 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These studies further suggest that CaMKIV may play an important role in anxiety-like behavior through its regulation of CREB since CREB mutant mice displayed alterations in emotional behavior [5,7,25].
CaMKIV Spec (like) Regulation (role) of Regulation (regulation) of CREB associated with anxiety disorder
1) Confidence 0.45 Published 2005 Journal Mol Pain Section Body Doc Link PMC1208947 Disease Relevance 0.95 Pain Relevance 0.04

General Comments

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