INT186168

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.35
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.54
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grin2b) embryo development (Grin2b)
Anatomy Link Frequency
synapses 2
Grin2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
5HT 45 98.76 Very High Very High Very High
nMDA receptor 43 94.12 High High
c fibre 3 90.72 High High
Dorsal horn neuron 3 89.88 High High
Thermal hyperalgesia 8 75.52 Quite High
Kinase C 5 71.72 Quite High
allodynia 14 66.48 Quite High
Spinal cord 33 56.12 Quite High
antagonist 13 50.88 Quite High
intrathecal 2 50.20 Quite High
Disease Link Frequency Relevance Heat
Nociception 27 82.32 Quite High
Hyperalgesia 13 75.52 Quite High
Neuropathic Pain 14 66.48 Quite High
Injury 14 56.68 Quite High
Pain 14 29.64 Quite Low
INFLAMMATION 21 5.00 Very Low Very Low Very Low
Cognitive Disorder 5 5.00 Very Low Very Low Very Low
Frailty 4 5.00 Very Low Very Low Very Low
Schizophrenia 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Only as the number of NR2B subunits is reduced do the synapses return toward normal function.
Negative_regulation (reduced) of Negative_regulation (number) of NR2B in synapses
1) Confidence 0.35 Published 2005 Journal Mol Pain Section Body Doc Link PMC1208948 Disease Relevance 0.54 Pain Relevance 0.76
m, 30 min) significantly prevented the 8-OH-DPAT-induced reduction of surface NR2B subunits (cluster density: 40.0 ± 2.7 clusters/50 ?
Negative_regulation (prevented) of Negative_regulation (reduction) of NR2B
2) Confidence 0.12 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427346 Disease Relevance 0 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox