INT186186

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Context Info
Confidence 0.08
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (LDLR, SCARB1) small molecule metabolic process (LDLR, SCARB1) plasma membrane (LDLR, SCARB1)
lipid metabolic process (LDLR, SCARB1) cell adhesion (SCARB1) cytoplasm (SCARB1)
Anatomy Link Frequency
macrophages 1
LDLR (Homo sapiens)
SCARB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 3 53.60 Quite High
Angina 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 14 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 18 96.64 Very High Very High Very High
Atherosclerosis 39 90.40 High High
Atherosclerotic Plaque 25 86.88 High High
Cv General 3 Under Development 4 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Myocardial Infarction 2 5.00 Very Low Very Low Very Low
Nicotine Addiction 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that SR-BI is regulated by proatherogenic stimuli such as hypoxia and mmLDL in human macrophages.
mmLDL Regulation (regulated) of SR-BI in macrophages associated with hypoxia
1) Confidence 0.08 Published 2005 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1215476 Disease Relevance 0.65 Pain Relevance 0.03

General Comments

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