INT186189

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Context Info
Confidence 0.14
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (LDLR, SCARB1) small molecule metabolic process (LDLR, SCARB1) plasma membrane (LDLR, SCARB1)
lipid metabolic process (LDLR, SCARB1) cell adhesion (SCARB1) cytoplasm (SCARB1)
Anatomy Link Frequency
macrophages 4
LDLR (Homo sapiens)
SCARB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 8 5.00 Very Low Very Low Very Low
Bile 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 78 97.84 Very High Very High Very High
Disorder Of Lipid Metabolism 36 84.16 Quite High
Atherosclerotic Plaque 50 74.16 Quite High
Hypoxia 28 66.04 Quite High
Cv General 3 Under Development 8 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Myocardial Infarction 4 5.00 Very Low Very Low Very Low
Nicotine Addiction 2 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the analysis confirms the previous findings that SR-BI expression is increased in response to 24 h mmLDL treatment of macrophages from both the subjects with atherosclerosis and the control subjects (p < 0.05 and p < 0.05, respectively).
mmLDL Positive_regulation (increased) of Gene_expression (expression) of SR-BI in macrophages associated with atherosclerosis
1) Confidence 0.14 Published 2005 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1215476 Disease Relevance 0.73 Pain Relevance 0
In this study we show that SR-BI expression in macrophages is increased in response to 24 h of mmLDL treatment.
mmLDL Positive_regulation (increased) of Gene_expression (expression) of SR-BI in macrophages
2) Confidence 0.14 Published 2005 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1215476 Disease Relevance 0.55 Pain Relevance 0

General Comments

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