INT186228

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.38
Pain Relevance 4.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
peripheral nerve 1
Timd4 (Mus musculus)
Pain Link Frequency Relevance Heat
nav1.8 140 100.00 Very High Very High Very High
Nav1.7 136 100.00 Very High Very High Very High
Peripheral nerve injury 12 99.52 Very High Very High Very High
allodynia 16 96.96 Very High Very High Very High
Neuropathic pain 52 96.84 Very High Very High Very High
nociceptor 44 93.88 High High
Acute pain 8 87.44 High High
Eae 31 84.40 Quite High
chung model 4 80.80 Quite High
Dopamine 22 75.00 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 150 100.00 Very High Very High Very High
Nervous System Injury 22 99.08 Very High Very High Very High
Neuropathic Pain 68 96.96 Very High Very High Very High
Pain 42 87.44 High High
Inflammatory Pain 28 84.40 Quite High
Nociception 14 69.04 Quite High
INFLAMMATION 14 37.04 Quite Low
Neuroma 2 27.12 Quite Low
Erythermalgia 2 14.40 Low Low
Sprains And Strains 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we study the induction and regulation of USVs in muscarinic and dopaminergic receptor knockout (KO) mice as well as wild-type controls during sexual behavior.
Regulation (regulation) of knockout associated with targeted disruption
1) Confidence 0.00 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2268741 Disease Relevance 0.27 Pain Relevance 0.04
To address the issue of compensatory up-regulation of Nav1.7 in Nav1.8 knockout we induced peripheral nerve injury in WT, Nav1.8 KO and DKO.
Regulation (regulation) of knockout in peripheral nerve associated with targeted disruption, nervous system injury, nav1.8, nav1.7 and peripheral nerve injury
2) Confidence 0.00 Published 2005 Journal Mol Pain Section Body Doc Link PMC1215513 Disease Relevance 1.82 Pain Relevance 2.36
In addition our results rule out Nav1.7 up-regulation in the Nav1.8 knockout as the reason behind the discrepancy between the finding of Kerr et al [17] and Lai et al [18].
Regulation (regulation) of knockout associated with targeted disruption, nav1.8 and nav1.7
3) Confidence 0.00 Published 2005 Journal Mol Pain Section Body Doc Link PMC1215513 Disease Relevance 1.29 Pain Relevance 2.35

General Comments

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