INT186345

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.19
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gast, Stat6) nucleus (Stat6) DNA binding (Stat6)
cytoplasm (Stat6) signal transducer activity (Stat6)
Gast (Mus musculus)
Stat6 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 21 88.40 High High
cytokine 159 79.28 Quite High
Inflammation 33 55.56 Quite High
Inflammatory response 6 33.68 Quite Low
Potency 6 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 591 96.36 Very High Very High Very High
Cold Sores 642 87.08 High High
Coronavirus Infection 3 65.52 Quite High
Severe Acute Respiratory Syndrome 3 65.04 Quite High
Influenza Virus Infection 12 63.28 Quite High
INFLAMMATION 39 55.56 Quite High
Viral Infection 45 25.24 Quite Low
Herpes Simplex Virus 42 5.00 Very Low Very Low Very Low
Apoptosis 33 5.00 Very Low Very Low Very Low
Cancer 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
concentrations, IL-4 has been shown to inhibit iNOS induction through STAT6 competition with STAT1 binding to the GAS element of the IRF-1 promoter region.
GAS Binding (binding) of STAT6
1) Confidence 0.03 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 1.04 Pain Relevance 0.07
Phosphorylated and homodimerized STAT6 binds to STAT binding elements (SBE), which includes GAS, and either trans-activates or inhibits transcription of the adjacent genes [212].
GAS Binding (binds) of STAT6
2) Confidence 0.03 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 0.11 Pain Relevance 0.15
concentrations, IL-4 has been shown to inhibit iNOS induction through STAT6 competition with STAT1 binding to the GAS element of the IRF-1 promoter region.
GAS Binding (binding) of STAT6
3) Confidence 0.03 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 1.04 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox