INT186357

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.09
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Irf1, Stat6) DNA binding (Irf1, Stat6) signal transduction (Stat6)
cytoplasm (Stat6) signal transducer activity (Stat6)
Irf1 (Mus musculus)
Stat6 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 14 88.40 High High
Inflammation 22 54.80 Quite High
cytokine 106 50.00 Quite Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 394 96.36 Very High Very High Very High
Cold Sores 428 87.08 High High
Coronavirus Infection 2 65.52 Quite High
Severe Acute Respiratory Syndrome 2 65.04 Quite High
Influenza Virus Infection 8 63.28 Quite High
INFLAMMATION 26 54.80 Quite High
Viral Infection 30 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 28 5.00 Very Low Very Low Very Low
Apoptosis 22 5.00 Very Low Very Low Very Low
Cancer 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
concentrations, IL-4 has been shown to inhibit iNOS induction through STAT6 competition with STAT1 binding to the GAS element of the IRF-1 promoter region.
IRF-1 Binding (binding) of STAT6
1) Confidence 0.04 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 1.04 Pain Relevance 0.07
concentrations, IL-4 has been shown to inhibit iNOS induction through STAT6 competition with STAT1 binding to the GAS element of the IRF-1 promoter region.
IRF-1 Binding (binding) of STAT6
2) Confidence 0.04 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 1.04 Pain Relevance 0.07

General Comments

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