INT186375

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, Il12b) extracellular region (TNF, Il12b) signal transduction (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
macrophages 2
TNF (Homo sapiens)
Il12b (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 1 65.76 Quite High
Inflammation 11 54.24 Quite High
cytokine 53 50.00 Quite Low
Central nervous system 7 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 214 98.04 Very High Very High Very High
Infection 197 84.12 Quite High
INFLAMMATION 13 54.24 Quite High
Viral Infection 15 53.28 Quite High
Herpes Simplex Virus 14 5.00 Very Low Very Low Very Low
Apoptosis 11 5.00 Very Low Very Low Very Low
Cancer 7 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low
Herpes Simplex Virus Infection 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In human macrophages, TNF has been shown to inhibit IL-12p40 production, but not p35 production, by a mechanism not involving NF-?
TNF Negative_regulation (inhibit) of Gene_expression (production) of IL-12p40 in macrophages
1) Confidence 0.03 Published 2005 Journal Virol J Section Body Doc Link PMC1215526 Disease Relevance 0.78 Pain Relevance 0.06

General Comments

This test has worked.

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