INT186457

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.47
First Reported 2005
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.53
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TAB1) protein complex (TAB1)
Anatomy Link Frequency
respiratory 1
TAB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 17 95.20 Very High Very High Very High
fluoxetine 1 87.08 High High
antidepressant 1 85.84 High High
corticosteroid 1 33.64 Quite Low
Arthritis 106 5.00 Very Low Very Low Very Low
Inflammation 20 5.00 Very Low Very Low Very Low
dexamethasone 7 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Respiratory Distress 16 98.24 Very High Very High Very High
Stress 6 94.00 High High
Cancer 36 88.08 High High
Pulmonary Alveolar Proteinosis 30 85.52 High High
Mucositis 1 83.52 Quite High
Dna Damage 1 77.36 Quite High
Renal Cancer 2 60.24 Quite High
Hepatocellular Cancer 1 55.60 Quite High
Liver Cancer 1 52.88 Quite High
Bronchitis 12 50.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase.
MAP3K7IP1 Binding (interaction) of
1) Confidence 0.47 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.65 Pain Relevance 0.18
The other seven genes, KIF1A, AQP12, FZD9, BAZ1B, LHPP, SYNGR1 and MAP3K7IP1 did not respond to the siRNA treatment (data not shown), suggesting that AR occupancy at these loci may be without functional consequences in cultured C4-2B cells.
MAP3K7IP1 Neg (not) Binding (respond) of
2) Confidence 0.10 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1904239 Disease Relevance 0.05 Pain Relevance 0
The infants with chronic respiratory distress of unknown cause had no mutations of SFTPB or SFTPC, and normal SP-B and SP-C in their lavages (Tab. 1).
Tab Neg (no) Binding (lavages) of in respiratory associated with respiratory distress
3) Confidence 0.03 Published 2005 Journal Respir Res Section Body Doc Link PMC1224872 Disease Relevance 0.83 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox