INT18647
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Autoradiographic localization of delta opioid receptors within the mesocorticolimbic dopamine system using radioiodinated [2-D-penicillamine, 5-D-penicillamine]enkephalin (125I-DPDPE). | |||||||||||||||
| |||||||||||||||
|
Autoradiographic localization of delta opiate receptors in rat and human brain. | |||||||||||||||
| |||||||||||||||
|
Co-localization of mu- and delta-opioid receptors on SK-N-SH cells has been studied by double labeling fluorescence experiments. | |||||||||||||||
| |||||||||||||||
|
K(+)-evoked acetylcholine release in the presence of TTX was inhibited by U50488, but not by DPDPE, suggesting the presence of kappa-opioid receptors on cholinergic terminals and the localization of delta-receptors on cortical interneurons. | |||||||||||||||
| |||||||||||||||
|
According to a cDNA microarray analysis, mRNA of protein kinase C-delta (PKC-delta), prostaglandin D synthase, and arachidonate release-relating enzymes were significantly overexpressed in the tumor tissue in comparison to the adjacent nontumor tissue. | |||||||||||||||
| |||||||||||||||
|
DISCUSSION: Both mu and delta-receptors are localized on nerve fibers within the cornea, which are accessible for topical opioid treatment. | |||||||||||||||
| |||||||||||||||
|
Thus, we conclude that pharmacological chaperones facilitate plasma membrane targeting of delta-opioid receptors by binding and stabilizing receptor precursors, thereby promoting their release from the stringent ER quality control. | |||||||||||||||
| |||||||||||||||
|
Phe27Cys polymorphism alters the maturation and subcellular localization of the human delta opioid receptor. | |||||||||||||||
| |||||||||||||||
|
The effects of mu, delta and kappa receptor agonists on both basal and LH-induced progesterone (P4) secretion were negligible. | |||||||||||||||
| |||||||||||||||
|
Cellular tolerance to delta-opioid agonists involves feedback-regulation of the function, concentration, and localization of the delta-opioid receptors (receptor desensitization) as well as of intracellular effectors (functional desensitization). | |||||||||||||||
| |||||||||||||||
|
However, it is not known whether the release of kappa- and delta-opioids is also concomitantly regulated. | |||||||||||||||
| |||||||||||||||
|
Using primary antisera directed toward cloned opioid receptors, delta-opioid receptor immunoreactivity was immunohistochemically localized in submucosal neurons and nerve fibers, but immunoreactivities to kappa- or mu-opioid receptors were not detected in the mucosa-submucosa. | |||||||||||||||
| |||||||||||||||
|
In situ hybridization histochemistry and immunocytochemistry were used to study localization and activity-dependent regulation of alpha, beta, gamma, and delta isoforms of type II calcium/calmodulin-dependent protein kinase (CaMKII) and their mRNAs in areas 17 and 18 of normal and monocularly deprived adult macaques. | |||||||||||||||
| |||||||||||||||
|
The actions of trimebutine [3,4,5-trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutylester] on the gastrointestinal tract are mediated via (i) an agonist effect on peripheral mu, kappa and delta opiate receptors and (ii) release of gastrointestinal peptides such as motilin and modulation of the release of other peptides, including vasoactive intestinal peptide, gastrin and glucagon. | |||||||||||||||
| |||||||||||||||
|
No significant correlations were found between the Log of Peak DeltaGH[CLON] response and any measure used in this study. | |||||||||||||||
| |||||||||||||||
|
Treatment in CM is a process of regulating and re-establishing the balance of Yin and Yang through reducing the redundancy of Yin or Yang () and reinforcing the deficiency of Yin or Yang () [3]. | |||||||||||||||
| |||||||||||||||
|
Using primary antisera directed toward cloned opioid receptors, delta-opioid receptor immunoreactivity was immunohistochemically localized in submucosal neurons and nerve fibers, but immunoreactivities to kappa- or mu-opioid receptors were not detected in the mucosa-submucosa. | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.