INT186508

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 8
Disease Relevance 7.41
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KCNN3)
Anatomy Link Frequency
SK-BR-3 1
MCF-7 1
BT-474 1
ZR-75-30 1
MDA-MB-231 1
KCNN3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 4 99.56 Very High Very High Very High
Neurotransmitter 5 98.84 Very High Very High Very High
Calcium channel 10 95.48 Very High Very High Very High
Migraine 76 91.64 High High
headache 6 54.32 Quite High
potassium channel 7 50.00 Quite Low
Pain 2 40.24 Quite Low
imagery 21 5.00 Very Low Very Low Very Low
member 8 14 5.00 Very Low Very Low Very Low
Kinase C 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 280 100.00 Very High Very High Very High
Channelopathies 2 92.76 High High
Headache 62 91.64 High High
Cancer 63 87.48 High High
Migraine With Aura 31 87.12 High High
Disease 24 85.96 High High
Chromosome Aberrations 14 83.92 Quite High
Spinocerebellar Ataxia Type 2 2 76.08 Quite High
Frailty 1 73.92 Quite High
Neurological Disease 6 70.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The KCNN3 gene acts to regulate the firing pattern of neurons via the generation of slow after-polarization and the regulation of intracellular calcium channels [17].
Regulation (regulate) of KCNN3 in neurons associated with calcium channel
1) Confidence 0.45 Published 2005 Journal BMC Med Genet Section Body Doc Link PMC1236929 Disease Relevance 1.46 Pain Relevance 1.03
Genetic, biochemical and pharmacologic studies of breast cancer have been greatly dependent on several commonly used model breast cancer cell lines: MCF-7, BT-474, SK-BR-3, T-47D, UACC-893, MDA-MB-231 and ZR-75-30.
Regulation (dependent) of SK-BR-3 in T-47D associated with breast cancer
2) Confidence 0.09 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1413994 Disease Relevance 0.85 Pain Relevance 0
Genetic, biochemical and pharmacologic studies of breast cancer have been greatly dependent on several commonly used model breast cancer cell lines: MCF-7, BT-474, SK-BR-3, T-47D, UACC-893, MDA-MB-231 and ZR-75-30.
Regulation (dependent) of SK-BR-3 in ZR-75-30 associated with breast cancer
3) Confidence 0.03 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1413994 Disease Relevance 0.85 Pain Relevance 0
Genetic, biochemical and pharmacologic studies of breast cancer have been greatly dependent on several commonly used model breast cancer cell lines: MCF-7, BT-474, SK-BR-3, T-47D, UACC-893, MDA-MB-231 and ZR-75-30.
Regulation (dependent) of SK-BR-3 in UACC-893 associated with breast cancer
4) Confidence 0.03 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1413994 Disease Relevance 0.85 Pain Relevance 0
Genetic, biochemical and pharmacologic studies of breast cancer have been greatly dependent on several commonly used model breast cancer cell lines: MCF-7, BT-474, SK-BR-3, T-47D, UACC-893, MDA-MB-231 and ZR-75-30.
Regulation (dependent) of SK-BR-3 in SK-BR-3 associated with breast cancer
5) Confidence 0.03 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1413994 Disease Relevance 0.85 Pain Relevance 0
Genetic, biochemical and pharmacologic studies of breast cancer have been greatly dependent on several commonly used model breast cancer cell lines: MCF-7, BT-474, SK-BR-3, T-47D, UACC-893, MDA-MB-231 and ZR-75-30.
Regulation (dependent) of SK-BR-3 in MCF-7 associated with breast cancer
6) Confidence 0.03 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1413994 Disease Relevance 0.85 Pain Relevance 0
Genetic, biochemical and pharmacologic studies of breast cancer have been greatly dependent on several commonly used model breast cancer cell lines: MCF-7, BT-474, SK-BR-3, T-47D, UACC-893, MDA-MB-231 and ZR-75-30.
Regulation (dependent) of SK-BR-3 in MDA-MB-231 associated with breast cancer
7) Confidence 0.03 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1413994 Disease Relevance 0.85 Pain Relevance 0
Genetic, biochemical and pharmacologic studies of breast cancer have been greatly dependent on several commonly used model breast cancer cell lines: MCF-7, BT-474, SK-BR-3, T-47D, UACC-893, MDA-MB-231 and ZR-75-30.
Regulation (dependent) of SK-BR-3 in BT-474 associated with breast cancer
8) Confidence 0.03 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1413994 Disease Relevance 0.85 Pain Relevance 0

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