INT186600

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SFRP5) signal transduction (SFRP5) extracellular space (SFRP5)
extracellular region (SFRP5) plasma membrane (SFRP5) embryo development (SFRP5)
SFRP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 2 5.56 Low Low
palliative 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Morphine 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Infliximab 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 4 99.60 Very High Very High Very High
Death 4 99.08 Very High Very High Very High
Cancer 102 98.76 Very High Very High Very High
Metastasis 10 82.16 Quite High
Ovarian Cancer 2 77.68 Quite High
Skin Cancer 2 75.28 Quite High
Pseudomonas Infection 2 74.20 Quite High
Prostate Cancer 8 72.32 Quite High
Toxicity 34 64.16 Quite High
Hepatotoxicity 18 57.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous experimental work in various rodent models provided evidence for efficacy of the recombinant antibody toxin scFv(FRP5)-ETA against ErbB2-expressing tumors [9,10,14,16,18,19].
Regulation (efficacy) of FRP5 associated with cancer
1) Confidence 0.06 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1242130 Disease Relevance 0.55 Pain Relevance 0
Efficacy of scFv(FRP5)-ETA in the treatment of ErbB2-overexpressing tumors has been established in numerous preclinical in vitro and in vivo studies.
Regulation (Efficacy) of FRP5 associated with cancer
2) Confidence 0.06 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1242130 Disease Relevance 1.04 Pain Relevance 0

General Comments

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