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Context Info
Confidence 0.22
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HLA-F)
Anatomy Link Frequency
immune cells 1
immune system 1
HLA-F (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 15 99.46 Very High Very High Very High
potassium channel 1 57.92 Quite High
Inflammatory mediators 1 7.76 Low Low
Inflammation 8 5.00 Very Low Very Low Very Low
iatrogenic 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Viremia 2 86.24 High High
Glaucoma 2 82.36 Quite High
Infection 169 81.48 Quite High
Disease 101 81.12 Quite High
Ocular Hypertension 2 79.12 Quite High
Hypergammaglobulinemia 1 74.48 Quite High
Sarcoma 195 72.60 Quite High
Hypotension 1 70.76 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 113 50.16 Quite High
Viral Infection 7 28.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These included genes encoding proteins involved in intracellular antigen processing and transport for eventual surface presentation to immune cells (PSMB8, TAP1), antigen presentation proteins, including HLA class I molecules (HLA-A, HLA-C, HLA-F, and HLA-G) and HLA class II molecules (HLA-DRB1, DRB4, DRB5, DPA1, and DPB1), cytokines involved in the recruitment of monocytes (SCYA3, SCYA4, CD14), and cytokine receptors (IL1R2, IL4R, and IL6R).
Gene_expression (molecules) of HLA-F in immune cells associated with cytokine
1) Confidence 0.22 Published 2005 Journal Genome Biol Section Body Doc Link PMC1242209 Disease Relevance 0.31 Pain Relevance 0.12
These pathogenic effects can promote active changes in the infected human host, such as to increase cytokine production or to suppress MHC Class I (MHC I) presentation of viral proteins to the immune system.
Gene_expression (presentation) of MHC Class I in immune system associated with cytokine
2) Confidence 0.11 Published 2005 Journal Virol J Section Body Doc Link PMC1243244 Disease Relevance 0.59 Pain Relevance 0.11

General Comments

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