INT186630

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Context Info
Confidence 0.19
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP10) extracellular space (MMP10) extracellular region (MMP10)
proteinaceous extracellular matrix (MMP10)
Anatomy Link Frequency
cornea 1
MMP10 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 2 79.68 Quite High
Inflammation 5 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 4 99.02 Very High Very High Very High
Corneal Disease 4 91.76 High High
Breast Cancer 1 89.92 High High
Adhesions 3 84.56 Quite High
Lymphatic System Cancer 2 69.04 Quite High
Targeted Disruption 4 57.36 Quite High
Wound Healing 5 51.60 Quite High
Cancer 2 30.80 Quite Low
Injury 2 10.56 Low Low
Carcinoma 1 5.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An intriguing subset of genes in the cornea signature has been studied in tumor metastasis models because these genes encode proteins that regulate cell-cell or cell-matrix interactions (TWIST, MMP10, SERPINB5, THBS1, CEACAM1, C4.4A).
Regulation (regulate) of MMP10 in cornea associated with metastasis
1) Confidence 0.19 Published 2005 Journal Genome Biol Section Body Doc Link PMC1242209 Disease Relevance 0.92 Pain Relevance 0.07

General Comments

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