INT186634

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Context Info
Confidence 0.33
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.44
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP10) extracellular space (MMP10) extracellular region (MMP10)
proteinaceous extracellular matrix (MMP10)
MMP10 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 6 96.92 Very High Very High Very High
Inflammation 6 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 10 100.00 Very High Very High Very High
Lymphatic System Cancer 2 99.36 Very High Very High Very High
Apoptosis 6 92.92 High High
Breast Cancer 1 91.60 High High
Metastasis 22 90.60 High High
Malignant Neoplastic Disease 3 87.40 High High
Wound Healing 5 81.28 Quite High
Corneal Disease 4 75.44 Quite High
Cancer 65 60.48 Quite High
Adenocarcinoma 17 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of MMP10 in transfected lymphoma cells has been shown to stimulate invasive activity in vitro and promote thymic lymphoma growth in an in vivo murine model [19].
Positive_regulation (Overexpression) of Gene_expression (Overexpression) of MMP10 associated with lymphatic system cancer
1) Confidence 0.33 Published 2005 Journal Genome Biol Section Body Doc Link PMC1242209 Disease Relevance 1.08 Pain Relevance 0.09
Some pro-angiogenic factors (IL18, IL15, MMP10, MMP28) as well as cell adhesion molecules (CEACAM 1, CEACAM 5, CEACAM 6) were also overexpressed.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of MMP10 associated with adhesions
2) Confidence 0.22 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2927995 Disease Relevance 0.37 Pain Relevance 0

General Comments

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