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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.01
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn2) extracellular region (Edn2)
Anatomy Link Frequency
endothelial cells 1
Edn2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 7 98.68 Very High Very High Very High
nociceptor 6 97.64 Very High Very High Very High
algogenic 4 89.96 High High
Brush evoked pain 2 71.20 Quite High
antagonist 4 67.52 Quite High
IPN 1 62.96 Quite High
dorsal root ganglion 22 25.60 Quite Low
Kinase C 2 23.44 Low Low
qutenza 40 18.08 Low Low
tetrodotoxin 3 6.80 Low Low
Disease Link Frequency Relevance Heat
Cancer 1 98.52 Very High Very High Very High
Pain 6 95.88 Very High Very High Very High
Hyperalgesia 5 90.64 High High
Osteoporosis 20 81.36 Quite High
Hypercalcemia 7 76.12 Quite High
Neuropathic Pain 4 71.20 Quite High
Inflammatory Pain 1 62.96 Quite High
Calcification 1 61.68 Quite High
Reprotox - General 1 1 58.48 Quite High
Nociception 7 50.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Considering 100% cross reactions of this kit for all ET subtypes including ET-1, ET-2 and ET-3 and performing our analysis without prior purification process it should be addressed that our measurements reflects total endothelin measurements, not ET-1 alone.
Gene_expression (subtypes) of ET-2
1) Confidence 0.09 Published 2005 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1242236 Disease Relevance 0.28 Pain Relevance 0
The endothelins, ET-1, ET-2 and ET-3, are vasoactive peptides, originally cloned from endothelial cells [1], but also produced by other cell types, including some tumor cells [2-5].
Gene_expression (produced) of ET-2 in endothelial cells associated with cancer
2) Confidence 0.05 Published 2007 Journal Mol Pain Section Body Doc Link PMC2206006 Disease Relevance 0.73 Pain Relevance 0.76

General Comments

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