INT186685

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn1, Il6) extracellular region (Edn1, Il6) aging (Il6)
cell-cell signaling (Edn1) cytoplasm (Edn1)
Edn1 (Rattus norvegicus)
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 14 98.64 Very High Very High Very High
Osteoporosis 40 94.60 High High
Endometriosis (extended) 4 78.72 Quite High
Calcification 2 65.60 Quite High
Disease 18 11.52 Low Low
Obesity 18 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hierl et al. [21] showed that ET-1 has a dose dependent stimulatory effect on IL-6 expression in human osteblastic cell (HOC) cultures.
ET-1 Regulation (effect) of Gene_expression (expression) of IL-6
1) Confidence 0.11 Published 2005 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1242236 Disease Relevance 0.61 Pain Relevance 0
ET-1's effect through the PG system [19,20] and IL-6 expression [21] are in favor of stimulating bone resorption.
ET-1 Regulation (effect) of Gene_expression (expression) of IL-6 associated with hypercalcemia
2) Confidence 0.07 Published 2005 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1242236 Disease Relevance 0.49 Pain Relevance 0

General Comments

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