INT186701

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (POLD4) nucleus (POLD4) nucleotidyltransferase activity (POLD4)
Anatomy Link Frequency
CAR 1
POLD4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 2 99.46 Very High Very High Very High
nMDA receptor 4 99.00 Very High Very High Very High
spinal dorsal horn 38 70.68 Quite High
adenocard 5 64.48 Quite High
Inflammation 35 48.96 Quite Low
cytokine 3 19.52 Low Low
Cholecystokinin 5 15.80 Low Low
Calcitonin gene-related peptide 5 14.88 Low Low
Neuropeptide 3 11.96 Low Low
Opioid 3 10.60 Low Low
Disease Link Frequency Relevance Heat
Injury 5 57.84 Quite High
INFLAMMATION 35 48.96 Quite Low
Nociception 20 5.00 Very Low Very Low Very Low
Pain 10 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Hyperalgesia 4 5.00 Very Low Very Low Very Low
Hypoalagesia 3 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 3 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, two genes (NR2B subunit of NMDA receptor and SstR2 somatostatin receptor), while being up-regulated in both CAR-P3 and CAR-P12 groups relative to CONT group, showed significantly lower levels of expression (by 0.5 and 0.7 fold respectively) in CAR-P3 rats as compared to those in CAR-P12 animals (Table 1).
Regulation (regulated) of P12 in CAR associated with nmda receptor and somatostatin
1) Confidence 0.44 Published 2005 Journal Mol Pain Section Body Doc Link PMC1242251 Disease Relevance 0.06 Pain Relevance 0.20

General Comments

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