INT186702

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Context Info
Confidence 0.65
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.29
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (POLD4) nucleus (POLD4) nucleotidyltransferase activity (POLD4)
Anatomy Link Frequency
CAR 2
POLD4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 71 91.80 High High
withdrawal 4 66.40 Quite High
spinal dorsal horn 76 56.04 Quite High
analgesia 2 41.72 Quite Low
Pain 18 30.08 Quite Low
Hyperalgesia 8 28.08 Quite Low
Lasting pain 2 15.88 Low Low
Spinal sensitization 2 14.60 Low Low
gABA 16 5.00 Very Low Very Low Very Low
cytokine 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 71 91.80 High High
Nociception 40 75.40 Quite High
Enzootic Bovine Leukosis 13 50.00 Quite Low
Hypersensitivity 10 41.84 Quite Low
Pain 20 30.08 Quite Low
Hyperalgesia 8 28.08 Quite Low
Lymphocytosis 33 5.00 Very Low Very Low Very Low
Infection 26 5.00 Very Low Very Low Very Low
Cancer 22 5.00 Very Low Very Low Very Low
Disease 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the CAR-P3 and CAR-P12 groups, the pups received a single injection of 0.25% CAR in sterile 0.9% saline (1 ?
Gene_expression (groups) of P12 in CAR
1) Confidence 0.65 Published 2005 Journal Mol Pain Section Body Doc Link PMC1242251 Disease Relevance 0.20 Pain Relevance 0.12
Then, the levels of the gene expressions between CAR-P3, CAR-P12, and CONT groups were compared employing one-way ANOVAs (with the false discovery rate (FDR) multiple testing error correction procedure of Benjamini and Hochberg [57] set at the P-value cutoff of 0.05) followed by Tukey's post-hoc tests (with the same P-cutoff value) in the implementation of GeneSpring GX software (Agilent, Palo Alto, CA).


Gene_expression (expressions) of P12 in CAR
2) Confidence 0.65 Published 2005 Journal Mol Pain Section Body Doc Link PMC1242251 Disease Relevance 0.09 Pain Relevance 0.05
The gag gene codes for the Pr44gag precursor, a polypeptide subsequently cleaved into the major non-glycosylated proteins of the viral particle (p15, p24 and p12) (Figure 2) [70,102-106].
Gene_expression (codes) of p12
3) Confidence 0.04 Published 2007 Journal Retrovirology Section Body Doc Link PMC1839114 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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