INT186769

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.30
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B-cells 2
Dep1 (Mus musculus)
IgG (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 103 94.72 High High
agonist 1 85.92 High High
cytokine 18 81.08 Quite High
Inflammatory mediators 3 66.56 Quite High
chemokine 10 26.32 Quite Low
adenocard 1 17.04 Low Low
tolerance 5 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Airway Remodeling 6 98.12 Very High Very High Very High
Hyperplasia 6 97.12 Very High Very High Very High
INFLAMMATION 96 94.72 High High
Asthma 106 91.12 High High
Stress 10 73.44 Quite High
Hypersensitivity 58 50.00 Quite Low
Nicotine Addiction 117 39.92 Quite Low
Pulmonary Disease 8 35.40 Quite Low
Injury 2 34.20 Quite Low
Adhesions 3 26.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IgE and IgG production by B-cells is elevated by DEP and cigarette smoke through the action of IL-4.
DEP Positive_regulation (elevated) of Gene_expression (production) of IgG in B-cells
1) Confidence 0.03 Published 2010 Journal Respir Res Section Body Doc Link PMC2831838 Disease Relevance 0.68 Pain Relevance 0.17
In addition, we have reported that DEP enhance antigen-specific production of IgE and IgG induced by intratracheal challenge with antigen in vivo [5,25].
DEP Positive_regulation (enhance) of Gene_expression (production) of IgG
2) Confidence 0.01 Published 2005 Journal Respir Res Section Body Doc Link PMC1242256 Disease Relevance 0.62 Pain Relevance 0.18

General Comments

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