INT186803

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Context Info
Confidence 0.67
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 1.54
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (TLR3) signal transduction (TLR3) endoplasmic reticulum (TLR3)
intracellular (TLR3) cytoplasm (TLR3)
Anatomy Link Frequency
pollen 2
cornea 1
endometrium 1
inferior 1
TLR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 21 89.04 High High
cytokine 25 71.64 Quite High
Inflammation 61 71.24 Quite High
chemokine 9 34.92 Quite Low
Inflammatory response 15 30.64 Quite Low
Antihistamine 12 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis 12 98.70 Very High Very High Very High
Rhinitis 100 98.12 Very High Very High Very High
Hypersensitivity 41 95.56 Very High Very High Very High
Herpes Simplex Virus 2 93.28 High High
Endometriosis (extended) 38 89.04 High High
Sinusitis 16 87.68 High High
INFLAMMATION 72 71.24 Quite High
Bacterial Respiratory Disease 1 63.16 Quite High
Asthma 24 51.20 Quite High
Wheal 4 48.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, endometriotic lesions in proliferative phase showed a significant increase of TLR3 mRNA expression (P < 0.05) when compared with the corresponding eutopic endometrium (figure 3A).
Transcription (expression) of TLR3 in endometrium associated with endometriosis
1) Confidence 0.67 Published 2008 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2543020 Disease Relevance 0.34 Pain Relevance 0.08
The mRNA expression of TLR3 was found to be elevated among patients with on-going symptomatic allergic rhinitis.
Transcription (expression) of TLR3 associated with rhinitis
2) Confidence 0.55 Published 2005 Journal Respir Res Section Body Doc Link PMC1243240 Disease Relevance 0.16 Pain Relevance 0.03
The expression of TLR3 mRNA was 318 ± 67 in controls (n = 15), 279 ± 31 in patients outside pollen season (n = 19) and 473 ± 80 in patients during pollen season (n = 11).
Transcription (expression) of TLR3 in pollen
3) Confidence 0.53 Published 2005 Journal Respir Res Section Body Doc Link PMC1243240 Disease Relevance 0 Pain Relevance 0
Real-time PCR demonstrated mRNA expression of TLR2, TLR3 and TLR4 in biopsies from the inferior turbinate of all tested subjects.
Transcription (expression) of TLR3 in inferior
4) Confidence 0.41 Published 2005 Journal Respir Res Section Body Doc Link PMC1243240 Disease Relevance 0.14 Pain Relevance 0
In human cornea, multiple groups have reported the expression of TLR3 [14,15], TLR4 [16,17], and TLR5 [18] mRNA and proteins.
Transcription (expression) of TLR3 in cornea
5) Confidence 0.39 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768757 Disease Relevance 0.32 Pain Relevance 0.07
The present study was designed to quantify mRNA and protein expressions of TLR2, TLR3 and TLR4 in the nasal mucosa of patients with seasonal allergic rhinitis, before and after pollen exposure, and to compare these findings with data derived from healthy volunteers.


Transcription (expressions) of TLR3 in pollen associated with rhinitis
6) Confidence 0.18 Published 2005 Journal Respir Res Section Body Doc Link PMC1243240 Disease Relevance 0.58 Pain Relevance 0.03

General Comments

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