INT186809

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Context Info
Confidence 0.65
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (TLR3) signal transduction (TLR3) endoplasmic reticulum (TLR3)
intracellular (TLR3) cytoplasm (TLR3)
Anatomy Link Frequency
endometrium 2
TLR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 21 89.52 High High
Inflammation 26 60.32 Quite High
Inflammatory response 1 6.12 Low Low
cytokine 10 5.00 Very Low Very Low Very Low
Antihistamine 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis 12 98.94 Very High Very High Very High
Rhinitis 25 98.32 Very High Very High Very High
Endometriosis (extended) 38 89.52 High High
INFLAMMATION 26 60.32 Quite High
Hypersensitivity 10 5.00 Very Low Very Low Very Low
Carcinoma 8 5.00 Very Low Very Low Very Low
Adenocarcinoma 7 5.00 Very Low Very Low Very Low
Asthma 6 5.00 Very Low Very Low Very Low
Uterine Diseases 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, endometriotic lesions in proliferative phase showed a significant increase of TLR3 mRNA expression (P < 0.05) when compared with the corresponding eutopic endometrium (figure 3A).
Positive_regulation (increase) of Transcription (expression) of TLR3 in endometrium associated with endometriosis
1) Confidence 0.65 Published 2008 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2543020 Disease Relevance 0.34 Pain Relevance 0.08
The mRNA expression of TLR3 was found to be elevated among patients with on-going symptomatic allergic rhinitis.
Positive_regulation (elevated) of Transcription (expression) of TLR3 associated with rhinitis
2) Confidence 0.53 Published 2005 Journal Respir Res Section Body Doc Link PMC1243240 Disease Relevance 0.16 Pain Relevance 0.03

General Comments

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