INT186871

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Context Info
Confidence 0.16
First Reported 2004
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 1.08
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (C4bpa) cytoplasm (C4bpa)
Anatomy Link Frequency
placenta 1
C4bpa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 2 87.52 High High
Bile 10 79.68 Quite High
monoamine 62 75.76 Quite High
Pyramidal cell 14 67.92 Quite High
Hippocampus 16 60.44 Quite High
ketamine 4 47.60 Quite Low
anesthesia 6 45.12 Quite Low
Central nervous system 20 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Neurobehavioral 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 20 91.44 High High
Aging 6 84.92 Quite High
Congenital Anomalies 5 82.88 Quite High
Toxicity 20 81.96 Quite High
Anxiety Disorder 24 73.20 Quite High
Shock 30 70.56 Quite High
Cognitive Disorder 10 64.28 Quite High
Stress Incontinence 1 20.36 Low Low
Death 4 5.00 Very Low Very Low Very Low
Exsanguination 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the open-field test, neither BPA nor NP exposure significantly affected the percentage of locomotion [F(3,32) = 0.271, p > 0.5] or the number of rearings [F(3,32) = 0.189, p > 0.5; data not shown].


Neg (neither) Regulation (affected) of BPA
1) Confidence 0.16 Published 2004 Journal Environ Health Perspect Section Body Doc Link PMC1247475 Disease Relevance 0.38 Pain Relevance 0
The mechanisms responsible for BPA’s effects remain unknown.
Regulation (responsible) of BPA
2) Confidence 0.13 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1257590 Disease Relevance 0.15 Pain Relevance 0.03
In the present study, we detected no statistically significant alterations by BPA or NP in the spontaneous activity and behaviors of rats in the open-field test at 8 weeks of age and in the elevated plus-maze test at 14 weeks of age.
Neg (no) Regulation (alterations) of BPA
3) Confidence 0.10 Published 2004 Journal Environ Health Perspect Section Body Doc Link PMC1247475 Disease Relevance 0.55 Pain Relevance 0.07
Therefore, in the present study, we examined the effects of estradiol and BPA, alone and in combination, on CA1 PSSD in adult ovariectomized (OVX) rats.
Spec (examined) Regulation (effects) of BPA
4) Confidence 0.08 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1257590 Disease Relevance 0 Pain Relevance 0.14
In the present study, we hypothesized that BPA-GA is transferred across the placenta to the fetus and then adversely affects the fetus by reactivation to BPA.
Regulation (affects) of BPA in placenta
5) Confidence 0.04 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2944077 Disease Relevance 0 Pain Relevance 0.13

General Comments

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