INT186878

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Context Info
Confidence 0.12
First Reported 2004
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 4.75
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (RTEL1) helicase activity (RTEL1) DNA binding (RTEL1)
Anatomy Link Frequency
B-cell 1
RTEL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 11 5.00 Very Low Very Low Very Low
Antihistamine 10 5.00 Very Low Very Low Very Low
positron emission tomography 6 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hodgkin's Disease 232 100.00 Very High Very High Very High
Lymphatic System Cancer 130 100.00 Very High Very High Very High
Immunodeficiency 1 98.00 Very High Very High Very High
Autoimmune Disease 1 95.84 Very High Very High Very High
Syndrome 2 93.36 High High
Celiac Disease 1 91.84 High High
Disease 46 91.20 High High
Cancer 99 83.24 Quite High
Herpes Simplex Virus Infection 1 82.96 Quite High
Epstein-barr Virus 1 81.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, the results of our case–control study suggest an association of pesticide exposures with NHL.
NHL Binding (association) of associated with hodgkin's disease
1) Confidence 0.12 Published 2004 Journal Environ Health Perspect Section Body Doc Link PMC1247516 Disease Relevance 0.74 Pain Relevance 0
Logistic regression for individual product groups with simultaneous adjustment for use of all other products revealed a significant positive association of NHL with mothballs (p = 0.03) and a marginally significant association with insecticides for flying insects/foggers (p = 0.07).
NHL Binding (association) of associated with hodgkin's disease
2) Confidence 0.12 Published 2004 Journal Environ Health Perspect Section Body Doc Link PMC1247516 Disease Relevance 0.26 Pain Relevance 0
When time of first use was analyzed for all household pesticide products combined, the association with NHL was significant only for pesticide use started during 1950–1969 (OR = 2.42; 95% CI, 1.16–5.02), whereas weaker associations were found for pesticide use started before 1950 or after 1969 (OR = 1.42 and 1.25, respectively; data not shown).
NHL Binding (association) of associated with hodgkin's disease
3) Confidence 0.12 Published 2004 Journal Environ Health Perspect Section Body Doc Link PMC1247516 Disease Relevance 0.33 Pain Relevance 0
This suggests that the association between mothball use and NHL merits further investigation.
NHL Binding (association) of associated with hodgkin's disease
4) Confidence 0.09 Published 2004 Journal Environ Health Perspect Section Body Doc Link PMC1247516 Disease Relevance 0.60 Pain Relevance 0
A finding that is relatively unique in this study is the increased risk of NHL associated with mothball use, although a dose response was not clearly demonstrated among users.
NHL Binding (associated) of associated with hodgkin's disease
5) Confidence 0.09 Published 2004 Journal Environ Health Perspect Section Body Doc Link PMC1247516 Disease Relevance 0.50 Pain Relevance 0
Apart from age, there are several risk factors associated to NHL:
NHL Binding (associated) of
6) Confidence 0.02 Published 2011 Journal Head Neck Oncol Section Body Doc Link PMC3022892 Disease Relevance 1.47 Pain Relevance 0
A multicenter phase II TST trial included 40 patients with indolent, follicular large cell, or transformed B-cell NHL who had progressed after RTX.
NHL Binding (indolent) of in B-cell associated with lymphatic system cancer
7) Confidence 0.02 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886324 Disease Relevance 0.86 Pain Relevance 0

General Comments

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