INT186984

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Context Info
Confidence 0.29
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.49
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (Abcg2) plasma membrane (Abcg2) nucleus (Abcg2)
Anatomy Link Frequency
face 2
Abcg2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
addiction 4 93.12 High High
alcohol 12 92.68 High High
cerebral cortex 8 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alcohol Addiction 2 93.12 High High
Chromosomal Instability 4 74.72 Quite High
Death 10 72.08 Quite High
Apoptosis 38 5.28 Low Low
Fetal Alcohol Syndrome 12 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 12 5.00 Very Low Very Low Very Low
Genomic Instability 8 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ethanol exposure, by suppressing ABCG2 expression, may decrease the survivability of neural stem cells in the face of subsequent toxic insults, including perhaps, subsequent episodes of ethanol exposure.


Negative_regulation (suppressing) of Gene_expression (expression) of ABCG2 in face
1) Confidence 0.29 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1249578 Disease Relevance 0.29 Pain Relevance 0.12
Finally, ethanol suppression of the expression of multi-drug resistance transporters like ABCG2 is also likely to be clinically significant.
Negative_regulation (suppression) of Gene_expression (expression) of ABCG2
2) Confidence 0.21 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1249578 Disease Relevance 0.20 Pain Relevance 0.14

General Comments

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