INT186989

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Akt1, Tert) nucleus (Akt1, Tert) cytoplasm (Akt1, Tert)
transport (Akt1) aging (Akt1) DNA binding (Tert)
Akt1 (Rattus norvegicus)
Tert (Rattus norvegicus)
Pain Link Frequency Relevance Heat
addiction 2 33.72 Quite Low
alcohol 6 33.28 Quite Low
tolerance 1 11.84 Low Low
cerebral cortex 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
gABA 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 19 100.00 Very High Very High Very High
Chromosomal Instability 2 71.76 Quite High
Death 5 67.84 Quite High
Ataxia 1 64.00 Quite High
Genomic Instability 4 50.24 Quite High
Alcohol Addiction 1 33.72 Quite Low
Aneuploidy 2 28.72 Quite Low
Fetal Alcohol Syndrome 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, TERT physically associates with the anti-apoptotic kinase AKT [86], and a reduction in TERT expression levels has the potential to render dividing cortical precursors susceptible to future apoptotic stimuli, (for example, see [41,87,88]), even if ethanol itself does not induce apoptosis.
kinase AKT Binding (associates) of TERT associated with apoptosis
1) Confidence 0.00 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1249578 Disease Relevance 0.61 Pain Relevance 0

General Comments

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