INT186997

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Context Info
Confidence 0.26
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.72
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PROM1) cilium (PROM1)
Anatomy Link Frequency
stem cell 4
PROM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cerebral cortex 4 78.16 Quite High
alcohol 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 67 99.98 Very High Very High Very High
Muscular Dystrophy 140 94.80 High High
Neuroblastoma 44 90.24 High High
Apoptosis 20 80.96 Quite High
Neurodegenerative Disease 6 75.84 Quite High
Cancer 24 70.84 Quite High
Death 10 59.28 Quite High
Disease Progression 14 39.52 Quite Low
Disease 26 26.00 Quite Low
Adhesions 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Linear regression analysis showed a significant negative correlation between age and CD133+CXCR4+CD34- levels (r2?
Negative_regulation (correlation) of Gene_expression (levels) of CD133
1) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2377332 Disease Relevance 0.54 Pain Relevance 0
Linear regression analysis showed a significant negative correlation between age and CD133+CXCR4+CD34- levels (r2?
Negative_regulation (correlation) of Gene_expression (age) of CD133
2) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2377332 Disease Relevance 0.54 Pain Relevance 0
On the other hand, ethanol induced asymmetric division in progenitor cells and decreased the cell surface expression of a number of stem cell markers, i.e., c-kit/CD117, Sca-1 (Ly6A/E), CD133/prominin-1 and the ABCG2 transporter.
Negative_regulation (decreased) of Gene_expression (expression) of CD133 in stem cell
3) Confidence 0.11 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1249578 Disease Relevance 0.48 Pain Relevance 0.08
Further, RA reduced the expression of some of the stem cell markers, including CD133, SOX2, and DLK1 (Fig. 1B).
Negative_regulation (reduced) of Gene_expression (expression) of CD133 in stem cell associated with rheumatoid arthritis
4) Confidence 0.09 Published 2010 Journal Nutrition Research and Practice Section Body Doc Link PMC2933444 Disease Relevance 1.16 Pain Relevance 0

General Comments

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