INT187051

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.04
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (RENBP)
Anatomy Link Frequency
blood 2
RENBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 10 100.00 Very High Very High Very High
alcohol 10 97.00 Very High Very High Very High
Inflammation 29 50.00 Quite Low
cytokine 13 5.00 Very Low Very Low Very Low
bradykinin 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
Neuronal nitric oxide synthase 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 93 100.00 Very High Very High Very High
Pressure And Volume Under Development 8 99.60 Very High Very High Very High
Hyperglycemia 38 99.30 Very High Very High Very High
Stress 34 97.60 Very High Very High Very High
Disorders Of Creatine Metabolism 12 96.12 Very High Very High Very High
Injury 5 77.28 Quite High
Apoptosis 89 76.32 Quite High
Obesity 25 74.32 Quite High
Crystal Associated Disease 10 71.12 Quite High
Chronic Renal Insufficiency 4 70.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAG and RBP models were adjusted for age, sex, BMI, systolic blood pressure, current/former worker status, alcohol ingestion, and diabetes. 41 ?
Positive_regulation (adjusted) of Gene_expression (models) of RBP in blood associated with diabetes mellitus and alcohol
1) Confidence 0.09 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253707 Disease Relevance 0.83 Pain Relevance 0.05
The baseline probability of having diabetes at this age (PopDM) using the coefficients in the Additional file 1 is:
Positive_regulation (diabetes) of Gene_expression (using) of age associated with diabetes mellitus
2) Confidence 0.09 Published 2008 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC2601038 Disease Relevance 0.40 Pain Relevance 0.08
Oxidative stress is probably a key event in endothelial dysfunction since inhibition of hyperglycemia, induced, ROS production prevents activation of the aldose reductase, hexosamine pathways, PKC activation, and AGE formation [77, 89].
Positive_regulation (activation) of Gene_expression (formation) of AGE associated with hyperglycemia, stress and kinase c
3) Confidence 0.03 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2903979 Disease Relevance 0.81 Pain Relevance 0.05

General Comments

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