INT187099

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.09
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd4, Itga1) plasma membrane (Cd4) enzyme binding (Cd4)
Anatomy Link Frequency
leukocyte 1
Cd4 (Mus musculus)
Itga1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 20 96.60 Very High Very High Very High
Arthritis 112 95.28 Very High Very High Very High
rheumatoid arthritis 13 84.64 Quite High
cytokine 35 75.44 Quite High
tolerance 1 11.84 Low Low
chemokine 8 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 127 96.84 Very High Very High Very High
Adhesions 15 92.12 High High
Rheumatoid Arthritis 13 84.64 Quite High
Immunization 8 44.92 Quite Low
INFLAMMATION 19 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Ankylosis 3 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Support for this model comes from studies showing loss or inhibition of CD44 and VLA-4 (very late antigen-4) interactions with their ligands that can reduce leukocyte rolling interactions and inhibit joint inflammation in animal models of arthritis [19,20].
antigen-4 Binding (interactions) of VLA-4 in leukocyte associated with inflammation and arthritis
1) Confidence 0.00 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257424 Disease Relevance 1.09 Pain Relevance 0.46

General Comments

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