INT187114

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCA1) small molecule metabolic process (ABCA1) Golgi apparatus (ABCA1)
intracellular (ABCA1) lipid metabolic process (ABCA1) extracellular region (TIMP2)
TIMP2 (Homo sapiens)
ABCA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 26 99.96 Very High Very High Very High
cytokine 2 72.80 Quite High
Inflammation 4 72.40 Quite High
rheumatoid arthritis 63 36.80 Quite Low
methotrexate 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Etanercept 1 5.00 Very Low Very Low Very Low
Leflunomide 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 72.40 Quite High
Apoptosis 3 57.52 Quite High
Metastasis 1 52.24 Quite High
Cancer 4 51.32 Quite High
Rheumatoid Arthritis 63 36.80 Quite Low
Arthropathy 7 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Autoimmune Disease 3 5.00 Very Low Very Low Very Low
Rupture 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, TIMP-1 is a preferential inhibitor of soluble MMPs, while TIMP-2 and TIMP-3 are also efficient inhibitors of the membrane-bound MMPs.
TIMP-2 Negative_regulation (inhibitors) of membrane-bound associated with metalloproteinase
1) Confidence 0.02 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257425 Disease Relevance 0.28 Pain Relevance 0.51

General Comments

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