INT187152

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Context Info
Confidence 0.36
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CXCR3) plasma membrane (CXCR3) cytoplasm (CXCR3)
signal transducer activity (CXCR3)
Anatomy Link Frequency
B cells 2
CXCR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 62 99.12 Very High Very High Very High
chemokine 82 86.64 High High
Osteoarthritis 19 78.84 Quite High
Inflammation 18 73.28 Quite High
cINOD 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Etanercept 1 5.00 Very Low Very Low Very Low
Adalimumab 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Infliximab 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 62 99.12 Very High Very High Very High
Systemic Lupus Erythematosus 39 92.88 High High
Osteoarthritis 20 78.84 Quite High
Disease 9 78.08 Quite High
Autoimmune Disease 2 75.36 Quite High
INFLAMMATION 19 73.28 Quite High
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In comparison with healthy individuals, in patients with RA a significant fraction of B cells showed a decreased expression of CXCR5 and CCR6 and increased levels of CXCR3.
Negative_regulation (decreased) of Positive_regulation (increased) of CXCR3 in B cells associated with rheumatoid arthritis
1) Confidence 0.36 Published 2005 Journal Arthritis Res Ther Section Abstract Doc Link PMC1257429 Disease Relevance 1.05 Pain Relevance 0.60

General Comments

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