INT187156

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.29
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 10
Disease Relevance 2.05
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD19)
Anatomy Link Frequency
B cells 5
macrophages 1
W6/32 1
NK cells 1
T cells 1
CD19 (Homo sapiens)
Pain Link Frequency Relevance Heat
Acupuncture 280 99.32 Very High Very High Very High
chemokine 82 89.04 High High
rheumatoid arthritis 63 86.64 High High
Osteoarthritis 19 82.44 Quite High
cytokine 71 75.04 Quite High
Inflammation 30 50.00 Quite Low
cINOD 4 36.56 Quite Low
Pain 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
analgesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 50 98.68 Very High Very High Very High
Recurrence 65 97.08 Very High Very High Very High
Chronic Fatigue Syndrome 70 88.00 High High
Rheumatoid Arthritis 83 86.64 High High
Osteoarthritis 20 82.44 Quite High
Systemic Lupus Erythematosus 39 81.80 Quite High
Lifespan 1 80.88 Quite High
Neuromyelitis Optica 28 76.76 Quite High
Autoimmune Disease 6 62.00 Quite High
Hyperthyroidism 1 59.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There are two possible explanations for this finding: Although rituximab causes complete depletion of CD19-positive peripheral B cells, it does not affect plasma cells.
CD19 Binding (depletion) of in B cells
1) Confidence 0.29 Published 2008 Journal Brain Section Body Doc Link PMC2577801 Disease Relevance 0.71 Pain Relevance 0
The CD19+ counts, which are closely associated with activity of B cells, significantly increased on day 8 after acupuncture, like variations of CD16+ and CD56+ counts.
CD19 Binding (associated) of in B cells associated with acupuncture
2) Confidence 0.28 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2176150 Disease Relevance 0 Pain Relevance 0.28
Cell counts of CD2+, CD4+, CD8+, CD11b+, CD16+, CD19+ and CD56+ were evaluated for variations in T cells, B cells, macrophages and NK cells after acupuncture treatment.
CD19 Binding (counts) of in T cells associated with acupuncture
3) Confidence 0.28 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2176150 Disease Relevance 0 Pain Relevance 0.13
T regulatory and NK cell gene sets both supported significant positive interaction with one or both of the CD19+ B cell sets.
CD19 Binding (interaction) of in B cell
4) Confidence 0.23 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2569951 Disease Relevance 0.29 Pain Relevance 0
Further, evidence suggests that even low circulating CD19 levels may be associated with poor response or returning disease [7].
CD19 Binding (associated) of associated with disease
5) Confidence 0.22 Published 2010 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2919195 Disease Relevance 0.42 Pain Relevance 0
Levels of CD27 expression used to define the various B cell subsets were defined by triple staining with CD19, CD20 and CD27 as shown in Fig. 2a.
CD19 Binding (staining) of in B cell
6) Confidence 0.17 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257429 Disease Relevance 0.63 Pain Relevance 0.41
Surface staining was measured by flow cytometry using fluorescence-labeled antibodies specific to CD19 (labeled with APC; clone HIB19; eBioscience) and HLA-ABC (labeled with FITC; clone W6/32; eBioscience) which reacts to HLA-A, B, and C.
CD19 Binding (specific) of in W6/32
7) Confidence 0.12 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2954825 Disease Relevance 0 Pain Relevance 0
Cell counts of CD2+, CD4+, CD8+, CD11b+, CD16+, CD19+ and CD56+ were evaluated for variations in T cells, B cells, macrophages and NK cells after acupuncture treatment.
CD19 Binding (counts) of in B cells associated with acupuncture
8) Confidence 0.10 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2176150 Disease Relevance 0 Pain Relevance 0.13
Cell counts of CD2+, CD4+, CD8+, CD11b+, CD16+, CD19+ and CD56+ were evaluated for variations in T cells, B cells, macrophages and NK cells after acupuncture treatment.
CD19 Binding (counts) of in macrophages associated with acupuncture
9) Confidence 0.10 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2176150 Disease Relevance 0 Pain Relevance 0.13
Cell counts of CD2+, CD4+, CD8+, CD11b+, CD16+, CD19+ and CD56+ were evaluated for variations in T cells, B cells, macrophages and NK cells after acupuncture treatment.
CD19 Binding (counts) of in NK cells associated with acupuncture
10) Confidence 0.10 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2176150 Disease Relevance 0 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox