INT187158

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Context Info
Confidence 0.38
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.60
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CXCL10) extracellular space (CXCL10) extracellular region (CXCL10)
cell-cell signaling (CXCL10)
CXCL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 44 99.56 Very High Very High Very High
rheumatoid arthritis 84 99.28 Very High Very High Very High
spinal inflammation 19 98.00 Very High Very High Very High
chemokine 111 97.60 Very High Very High Very High
Infliximab 1 51.44 Quite High
Etanercept 1 50.48 Quite High
cytokine 27 50.36 Quite High
Inflammation 32 50.00 Quite Low
Adalimumab 1 49.28 Quite Low
cINOD 3 39.52 Quite Low
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 39 99.66 Very High Very High Very High
Arthritis 27 99.56 Very High Very High Very High
Rheumatoid Arthritis 84 99.28 Very High Very High Very High
Low Back Pain 19 98.00 Very High Very High Very High
Seronegative Spondarthritis 17 96.60 Very High Very High Very High
Rheumatic Diseases 2 94.04 High High
Infectious Arthritis 1 60.64 Quite High
Cancer 5 54.48 Quite High
Necrosis 5 54.00 Quite High
INFLAMMATION 34 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared with CA patients, the median synovial CXCL10 levels were significantly enhanced in patients with RA (P < 10-7), in patients with AS (P < 10-4) and in patients with PsA (P < 10-4).
Positive_regulation (enhanced) of Positive_regulation (synovial) of CXCL10 associated with spinal inflammation, rheumatoid arthritis and arthritis
1) Confidence 0.38 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779382 Disease Relevance 1.19 Pain Relevance 0.67
Only a single patient with SLE showed slightly increased levels of CXCL10.


Positive_regulation (levels) of Positive_regulation (increased) of CXCL10 associated with systemic lupus erythematosus
2) Confidence 0.32 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257429 Disease Relevance 0.41 Pain Relevance 0.37

General Comments

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