INT187172

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.89
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP9) extracellular space (MMP9) extracellular region (MMP9)
proteinaceous extracellular matrix (MMP9) extracellular matrix organization (MMP9) protein complex (MMP9)
Anatomy Link Frequency
monocytes 1
fibroblasts 1
RPS3AP9 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 156 100.00 Very High Very High Very High
Rheumatoid arthritis 152 100.00 Very High Very High Very High
spinal inflammation 30 5.00 Very Low Very Low Very Low
osteoarthritis 16 5.00 Very Low Very Low Very Low
inflammatory 8 5.00 Very Low Very Low Very Low
NSAID 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 152 100.00 Very High Very High Very High
Low Back Pain 30 5.00 Very Low Very Low Very Low
Frailty 18 5.00 Very Low Very Low Very Low
Cancer 12 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AP9 had some inhibitory effect on the secretion of pro-MMP9 (control, 33.7 ± 18.5%; RA, 31.8 ± 16.2), MMP-9 (control, 41.9 ± 5.8%; RA, 43.8 ± 5.1%) and MMP-2 (control, 100%; RA, 63.9 ± 6.2%) in the co-culture of human monocytes and fibroblasts in both the normal control and RA groups (Fig. 4c).
AP9 Negative_regulation (effect) of MMP-9 in monocytes associated with metalloproteinase and rheumatoid arthritis
1) Confidence 0.00 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257431 Disease Relevance 0.44 Pain Relevance 0.60
AP9 had some inhibitory effect on the secretion of pro-MMP9 (control, 33.7 ± 18.5%; RA, 31.8 ± 16.2), MMP-9 (control, 41.9 ± 5.8%; RA, 43.8 ± 5.1%) and MMP-2 (control, 100%; RA, 63.9 ± 6.2%) in the co-culture of human monocytes and fibroblasts in both the normal control and RA groups (Fig. 4c).
AP9 Negative_regulation (effect) of MMP-9 in fibroblasts associated with metalloproteinase and rheumatoid arthritis
2) Confidence 0.00 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257431 Disease Relevance 0.44 Pain Relevance 0.60

General Comments

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