INT187184

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Context Info
Confidence 0.27
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (PPIA) isomerase activity (PPIA) protein folding (PPIA)
cytosol (PPIA) extracellular region (PPIA) nucleus (PPIA)
Anatomy Link Frequency
joints 1
PPIA (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 76 99.60 Very High Very High Very High
Inflammation 4 99.04 Very High Very High Very High
metalloproteinase 78 78.84 Quite High
antagonist 1 63.12 Quite High
spinal inflammation 15 5.00 Very Low Very Low Very Low
Osteoarthritis 8 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 76 99.60 Very High Very High Very High
INFLAMMATION 5 99.04 Very High Very High Very High
Hepatocellular Cancer 2 61.92 Quite High
Cancer 6 32.76 Quite Low
Atherosclerotic Plaque 1 15.16 Low Low
Low Back Pain 15 5.00 Very Low Very Low Very Low
Frailty 9 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If CyPA is released into the medium during inflammation, it is highly possible that it could act as a ligand of CD147 to induce the accumulation of inflammatory cells that highly express CD147 in the joints of RA patients.
Localization (released) of CyPA in joints associated with inflammation and rheumatoid arthritis
1) Confidence 0.27 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257431 Disease Relevance 0.64 Pain Relevance 0.37

General Comments

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