INT187185

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.61
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (BSG) small molecule metabolic process (BSG) plasma membrane (BSG)
Anatomy Link Frequency
synovium 1
BSG (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 77 98.36 Very High Very High Very High
Osteoarthritis 8 97.56 Very High Very High Very High
spinal inflammation 16 97.28 Very High Very High Very High
metalloproteinase 78 95.00 High High
member 8 1 86.84 High High
cytokine 1 74.64 Quite High
Inflammation 4 59.40 Quite High
cINOD 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 3 100.00 Very High Very High Very High
Rheumatoid Arthritis 78 98.36 Very High Very High Very High
Frailty 9 97.56 Very High Very High Very High
Low Back Pain 16 97.28 Very High Very High Very High
Cancer 15 96.16 Very High Very High Very High
Epstein-barr Virus 12 94.48 High High
Infection 3 94.20 High High
Adhesions 1 81.80 Quite High
Necrosis 4 76.00 Quite High
INFLAMMATION 5 59.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, CD147 (basigin; EMMPRIN), the second most abundant CD in our cDNA library, is a major mediator of malignant cell behavior in the human, and is regulated by several membrane-associated cofactors, including annexin II (containing one EST) and caveolin-1 [39].
Regulation (regulated) of CD147 associated with malignant neoplastic disease
1) Confidence 0.44 Published 2006 Journal BMC Genomics Section Body Doc Link PMC1522023 Disease Relevance 0.78 Pain Relevance 0.12
The immunoreactivity of CD147 was more intense and more widespread in RA synovium than in OA and AS synovium, and the expression of CD147 correlated with MMP-1 expression.
Regulation (immunoreactivity) of CD147 in synovium associated with spinal inflammation, metalloproteinase, rheumatoid arthritis and osteoarthritis
2) Confidence 0.24 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257431 Disease Relevance 0.82 Pain Relevance 0.54

General Comments

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