INT187233

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Context Info
Confidence 0.12
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk8, Jun) nucleus (Mapk8, Jun) mitochondrion (Mapk8)
DNA binding (Jun) cytoplasm (Mapk8) signal transduction (Mapk8)
Anatomy Link Frequency
nucleus 2
Mapk8 (Mus musculus)
Jun (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 36 97.84 Very High Very High Very High
Arthritis 54 91.24 High High
Inflammation 24 78.40 Quite High
rheumatoid arthritis 33 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Freund adjuvant 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 4 97.44 Very High Very High Very High
Arthritis 64 91.24 High High
Cancer 3 90.96 High High
Necrosis 3 90.48 High High
INFLAMMATION 28 78.40 Quite High
Hypercalcemia 11 33.04 Quite Low
Rheumatoid Arthritis 33 5.00 Very Low Very Low Very Low
Immunization 6 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 5 5.00 Very Low Very Low Very Low
Autoimmune Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B to the nucleus and the activation of c-Jun N-terminal kinase (JNK), which leads to the activation of AP-1 [32,33].
Positive_regulation (activation) of JNK Positive_regulation (activation) of AP-1 in nucleus
1) Confidence 0.12 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257432 Disease Relevance 0.92 Pain Relevance 0.37

General Comments

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