INT187287

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Context Info
Confidence 0.16
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.96
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HEY1) protein binding transcription factor activity (HEY1) DNA binding (HEY1)
transcription factor binding (HEY1) cytoplasm (HEY1)
HEY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 32 95.92 Very High Very High Very High
rheumatoid arthritis 141 84.52 Quite High
Infliximab 6 74.52 Quite High
Etanercept 8 64.80 Quite High
imagery 5 61.64 Quite High
antagonist 1 61.28 Quite High
Inflammation 22 32.88 Quite Low
fibrosis 9 11.60 Low Low
Osteoarthritis 9 5.00 Very Low Very Low Very Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 4 Under Development 192 100.00 Very High Very High Very High
Pulmonary Disease 71 100.00 Very High Very High Very High
Heart Failure 62 100.00 Very High Very High Very High
Chronic Renal Failure 56 100.00 Very High Very High Very High
Hypertrophy 8 100.00 Very High Very High Very High
Apoptosis 1 95.76 Very High Very High Very High
Disease 29 84.84 Quite High
Rheumatoid Arthritis 143 84.52 Quite High
Targeted Disruption 4 59.84 Quite High
Coronary Heart Disease 18 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Key features of the CHF phenotype, including pulmonary edema, negative inotropy, ventricular dilatation and hypertrophy, endothelial dysfunction, reduced myocardial ?
Negative_regulation (reduced) of Gene_expression (phenotype) of CHF associated with hypertrophy and cv general 4 under development
1) Confidence 0.16 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257451 Disease Relevance 1.29 Pain Relevance 0.45
5.1 How do self-perceived symptoms, care needs, caregiver burden, preferences with regard to life-sustaining treatments, end-of-life care communication and management of patients with severe to very severe COPD, CHF and CRF change over time according to the patients and their closest relatives?
Negative_regulation (severe) of Gene_expression (change) of CHF associated with chronic renal failure, pulmonary disease and heart failure
2) Confidence 0.14 Published 2008 Journal BMC Palliat Care Section Body Doc Link PMC2391145 Disease Relevance 1.67 Pain Relevance 0

General Comments

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