INT187288

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Context Info
Confidence 0.17
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 8.42
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HEY1) protein binding transcription factor activity (HEY1) DNA binding (HEY1)
transcription factor binding (HEY1) cytoplasm (HEY1)
HEY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 45 99.52 Very High Very High Very High
cytokine 65 99.28 Very High Very High Very High
rheumatoid arthritis 282 96.84 Very High Very High Very High
methotrexate 6 88.20 High High
cva 13 56.56 Quite High
imagery 11 5.12 Low Low
Osteoarthritis 18 5.00 Very Low Very Low Very Low
fibrosis 18 5.00 Very Low Very Low Very Low
Etanercept 16 5.00 Very Low Very Low Very Low
metalloproteinase 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 4 Under Development 384 100.00 Very High Very High Very High
Pulmonary Disease 142 100.00 Very High Very High Very High
Heart Failure 124 100.00 Very High Very High Very High
Chronic Renal Failure 112 100.00 Very High Very High Very High
Frailty 65 100.00 Very High Very High Very High
INFLAMMATION 45 99.52 Very High Very High Very High
Coronary Heart Disease 36 97.48 Very High Very High Very High
Rheumatoid Arthritis 286 96.84 Very High Very High Very High
Hyperhomocysteinemia 6 96.12 Very High Very High Very High
Death 6 92.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
2.1 How are the self-perceived symptoms of patients with severe to very severe COPD, CHF or CRF perceived by their closest relatives?
Positive_regulation (severe) of Gene_expression (severe) of CHF associated with chronic renal failure, pulmonary disease and heart failure
1) Confidence 0.17 Published 2008 Journal BMC Palliat Care Section Body Doc Link PMC2391145 Disease Relevance 1.91 Pain Relevance 0
2.1 How are the self-perceived symptoms of patients with severe to very severe COPD, CHF or CRF perceived by their closest relatives?
Positive_regulation (perceived) of Gene_expression (severe) of CHF associated with chronic renal failure, pulmonary disease and heart failure
2) Confidence 0.17 Published 2008 Journal BMC Palliat Care Section Body Doc Link PMC2391145 Disease Relevance 1.93 Pain Relevance 0
In patients with overt CHF, levels of inflammatory cytokines (TNF-?
Positive_regulation (overt) of Gene_expression (overt) of CHF associated with inflammation, cv general 4 under development and cytokine
3) Confidence 0.17 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257451 Disease Relevance 2.37 Pain Relevance 0.72
CHF with preserved systolic function
Positive_regulation (preserved) of Gene_expression (preserved) of CHF associated with cv general 4 under development
4) Confidence 0.17 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257451 Disease Relevance 1.81 Pain Relevance 0.17
In more detail, there is a distinction between the CHF and HC groups in their absolute spectral amplitudes in interval VI, which is significant in response to ACh (Fig. 5a) but not to SNP (Fig. 5c).
Positive_regulation (distinction) of Gene_expression (groups) of CHF associated with frailty
5) Confidence 0.02 Published 2008 Journal Microvasc Res Section Body Doc Link PMC2666799 Disease Relevance 0.40 Pain Relevance 0

General Comments

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