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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.48
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) cytosol (ATIC)
mitochondrion (ATIC) small molecule metabolic process (ATIC) plasma membrane (Ros1)
ATIC (Homo sapiens)
Ros1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 44 98.04 Very High Very High Very High
cINOD 2 86.88 High High
Inflammation 34 82.28 Quite High
Inflammatory response 7 50.76 Quite High
Inflammatory mediators 11 50.00 Quite Low
ischemia 3 19.76 Low Low
COX-2 inhibitor 2 15.36 Low Low
Nerve growth factor 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 14 93.68 High High
Drug Induced Neurotoxicity 4 93.12 High High
Apoptosis 3 93.12 High High
Disease 36 91.76 High High
INFLAMMATION 53 86.48 High High
Cognitive Disorder 2 81.36 Quite High
Toxicity 7 79.92 Quite High
Alzheimer's Dementia 15 77.52 Quite High
Injury 2 65.60 Quite High
Death 6 34.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hence our findings described in this study, documenting inhibition of production of both NO and ROS by AICAR, suggest AICAR/AMPK-mediated protection against cytokine/A?
AICAR Negative_regulation (inhibition) of Gene_expression (production) of ROS associated with cytokine
1) Confidence 0.00 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1262754 Disease Relevance 1.48 Pain Relevance 0.39

General Comments

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