INT187585

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Context Info
Confidence 0.36
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Crebbp) nucleus (Crebbp) DNA binding (Crebbp)
protein complex (Crebbp) transcription factor binding (Crebbp) cytoplasm (Crebbp)
Crebbp (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 9 24.24 Low Low
agonist 21 5.00 Very Low Very Low Very Low
aspirin 7 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Peripheral nervous system 3 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Embryonic Lethality 1 54.80 Quite High
Placental Insufficiency 1 52.64 Quite High
Obesity 404 50.00 Quite Low
Body Weight 213 46.32 Quite Low
Disorder Of Lipid Metabolism 36 42.60 Quite Low
Metabolic Disorder 27 5.00 Very Low Very Low Very Low
Diabetes Mellitus 24 5.00 Very Low Very Low Very Low
Cardiovascular Disease 24 5.00 Very Low Very Low Very Low
Cancer 23 5.00 Very Low Very Low Very Low
Prostate Cancer 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin, blocking recruitment of p300/CBP to this domain.
p300/CBP Binding (recruitment) of
1) Confidence 0.36 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2955614 Disease Relevance 0 Pain Relevance 0
However, E2 significantly decreased Wy14,643-induced CBP association in the presence of ER?
CBP Binding (association) of
2) Confidence 0.25 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0 Pain Relevance 0
However, only AIB1, CBP, MAK, BRCA1, and ?
CBP Binding (However) of
3) Confidence 0.22 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2518564 Disease Relevance 0 Pain Relevance 0
recruitment of coactivators such as CBP (Figure 6(c)).
CBP Binding (recruitment) of
4) Confidence 0.19 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0 Pain Relevance 0
Ligand-induced conformational changes that allow recruitment of coactivators, such as CBP and the dissociation of corepressors such as NCoR, are obligatory for transactivation by PPAR?.
CBP Binding (recruitment) of
5) Confidence 0.19 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0 Pain Relevance 0
Two coactivators that have histone acetyltransferase activity, steroid receptor coactivator-1 (SRC-1) and CREB binding protein/p300 (CBP), can bind to PPARs in a ligand-dependent manner.
CBP Binding (bind) of
6) Confidence 0.05 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266036 Disease Relevance 0.11 Pain Relevance 0

General Comments

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