INT187619

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 3.17
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ppara) nucleus (Ppara) DNA binding (Ppara)
Anatomy Link Frequency
luteal cells 2
Ppara (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 108 99.76 Very High Very High Very High
ischemia 15 92.56 High High
Inflammation 27 88.32 High High
cINOD 33 67.32 Quite High
metalloproteinase 3 39.36 Quite Low
antagonist 7 32.76 Quite Low
cva 9 15.36 Low Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 12 97.68 Very High Very High Very High
Coronary Heart Disease 14 95.44 Very High Very High Very High
Reperfusion Injury 3 93.32 High High
Cv Unclassified Under Development 15 92.56 High High
Diabetes Mellitus 10 91.60 High High
Apoptosis 186 91.08 High High
Stress 22 90.36 High High
INFLAMMATION 39 88.32 High High
Dyslipidemia /

Combined Dyslipidemia

3 86.68 High High
Body Weight 14 82.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ligands enhance binding of PPAR?
Positive_regulation (enhance) of PPAR Binding (binding) of
1) Confidence 0.65 Published 2010 Journal PPAR Research Section Body Doc Link PMC2938460 Disease Relevance 0.39 Pain Relevance 0
Ligand-activated PPAR?
Positive_regulation (activated) of PPAR Binding (Ligand) of
2) Confidence 0.47 Published 2010 Journal PPAR Research Section Body Doc Link PMC2938460 Disease Relevance 0.66 Pain Relevance 0.09
activator in an in vitro system, the involvement of PPAR?
Positive_regulation (activator) of PPAR Binding (involvement) of
3) Confidence 0.46 Published 2010 Journal PPAR Research Section Body Doc Link PMC2910468 Disease Relevance 0.54 Pain Relevance 0.20
may be essential for normal cardiac development, but that treatment with exogenous PPAR-?
Positive_regulation (essential) of PPAR Binding (exogenous) of
4) Confidence 0.44 Published 2009 Journal PPAR Research Section Body Doc Link PMC2696219 Disease Relevance 0.96 Pain Relevance 0.26
are mediated through enhanced binding of PPAR to the promoter of 14-3-3?
Positive_regulation (enhanced) of PPAR Binding (binding) of
5) Confidence 0.43 Published 2010 Journal PPAR Research Section Abstract Doc Link PMC2938460 Disease Relevance 0.53 Pain Relevance 0.05
Progesterone production by bovine luteal cells treated with the endogenous ligand for PPAR?
Positive_regulation (treated) of PPAR Binding (ligand) of in luteal cells
6) Confidence 0.17 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266036 Disease Relevance 0 Pain Relevance 0.06
The binding affinity of the PPAR/RXR heterodimer is greatly enhanced if the nucleotide between the two hexamers is an adenine, and when there is an AA/TCT sequence 5' of the PPRE (reviewed in [4,5,32]).
Positive_regulation (enhanced) of PPAR Binding (affinity) of
7) Confidence 0.16 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266036 Disease Relevance 0 Pain Relevance 0.06
In addition to the PPRE, the 5' flanking region has been shown to be important for PPAR binding to DNA, especially PPAR?
Positive_regulation (important) of PPAR Binding (binding) of
8) Confidence 0.16 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266036 Disease Relevance 0 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox