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Context Info
Confidence 0.12
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.63
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (SARDH) oxidoreductase activity (SARDH) biological_process (SARDH)
cytoplasm (SARDH)
Anatomy Link Frequency
smooth muscle 1
nasal 1
SARDH (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 48 100.00 Very High Very High Very High
corticosteroid 14 96.52 Very High Very High Very High
primary afferent fibers 2 94.36 High High
agonist 8 86.36 High High
Antihistamine 23 86.00 High High
medulla 6 83.44 Quite High
Action potential 3 70.84 Quite High
Onset of action 13 64.04 Quite High
Inflammation 24 61.04 Quite High
antagonist 22 59.12 Quite High
Disease Link Frequency Relevance Heat
Rhinitis 101 100.00 Very High Very High Very High
Anaplastic Astrocytoma 2 96.92 Very High Very High Very High
Atelectasis 2 88.56 High High
Bronchospasm 3 87.84 High High
INFLAMMATION 26 61.04 Quite High
Pressure And Volume Under Development 1 34.92 Quite Low
Hypersensitivity 24 32.68 Quite Low
Cough 77 5.00 Very Low Very Low Very Low
Disease 13 5.00 Very Low Very Low Very Low
Sneezing 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with a history of SAR and symptomatic while exposed to ragweed pollen in an environmental exposure chamber (EEC) were randomized to 2 sprays per nostril of azelastine nasal spray (137 ?
Positive_regulation (history) of SAR in nasal associated with rhinitis
1) Confidence 0.12 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2621402 Disease Relevance 0.22 Pain Relevance 0.37
SAR activation also inhibits cholinergic drive to the airway smooth muscle, resulting in a reduction in airway tone [8].
Positive_regulation (activation) of SAR in smooth muscle
2) Confidence 0.02 Published 2005 Journal Cough Section Body Doc Link PMC1266044 Disease Relevance 0.24 Pain Relevance 0.12
We have demonstrated a cross-desensitization between hHK-1 and [Sar9, Met (O2)11] SP substantiating NK1-receptor activation and desensitization by hHK-1.
Positive_regulation (activation) of Sar9 associated with substance p
3) Confidence 0.00 Published 2010 Journal Respir Res Section Body Doc Link PMC2959027 Disease Relevance 0.17 Pain Relevance 0.39

General Comments

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