INT187665

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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.82
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (HSD11B1) oxidoreductase activity (HSD11B1) endoplasmic reticulum (HSD11B1)
HSD11B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 1 34.64 Quite Low
Angina 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 293 100.00 Very High Very High Very High
Metabolic Disorder 1 100.00 Very High Very High Very High
Hyperlipidemia 25 98.16 Very High Very High Very High
Coronary Artery Disease 16 70.00 Quite High
Cardiovascular Disease 8 53.20 Quite High
Diabetes Mellitus 30 34.24 Quite Low
Body Weight 21 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 8 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with our results, Seki et al. [16] referred the decrease of serum total cholesterol level in quinazoline derivative-treated rats to reduction in serum VLDL-C and LDL-C rather than HDL-C levels.
Negative_regulation (decrease) of Negative_regulation (reduction) of HDL associated with disorder of lipid metabolism
1) Confidence 0.42 Published 2005 Journal Lipids Health Dis Section Body Doc Link PMC1266394 Disease Relevance 0.82 Pain Relevance 0
It indicated that HDL metabolic disorders and HDL maturation are blocked in the TG ?
Negative_regulation (blocked) of Negative_regulation (disorders) of HDL associated with metabolic disorder and disorder of lipid metabolism
2) Confidence 0.29 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2920871 Disease Relevance 2.00 Pain Relevance 0

General Comments

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