INT187668

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (PLOD1) signal transduction (GNRH1) extracellular space (GNRH1)
extracellular region (GNRH1) endoplasmic reticulum (PLOD1) cell-cell signaling (GNRH1)
Anatomy Link Frequency
ovaries 2
GNRH1 (Homo sapiens)
PLOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 44 5.00 Very Low Very Low Very Low
agonist 34 5.00 Very Low Very Low Very Low
corticosteroid 8 5.00 Very Low Very Low Very Low
endometriosis 7 5.00 Very Low Very Low Very Low
dexamethasone 5 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Embryo Loss 1 65.24 Quite High
Reprotox - General 3 38 50.00 Quite Low
Polyploidy 4 49.76 Quite Low
Endometriosis (extended) 13 5.00 Very Low Very Low Very Low
Polycystic Ovary Syndrome 12 5.00 Very Low Very Low Very Low
Obesity 11 5.00 Very Low Very Low Very Low
Ovarian Hyperstimulation Syndrome 11 5.00 Very Low Very Low Very Low
Spontaneous Abortion 9 5.00 Very Low Very Low Very Low
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
Edema 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment with FSH initially attenuated the response of LH to GnRH via the production of GnSAF from the ovaries, while around the midfollicular phase, the rising concentrations of E2 were able to overcome the attenuating effect of GnSAF and increase pituitary sensitivity to GnRH.
Negative_regulation (attenuated) of GnRH Positive_regulation (response) of LH in ovaries
1) Confidence 0.06 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0.07 Pain Relevance 0

General Comments

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