INT187670

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Context Info
Confidence 0.16
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CYP19A1) endosome (FSHR) small molecule metabolic process (CYP19A1)
endoplasmic reticulum (CYP19A1) plasma membrane (FSHR) cytoplasm (CYP19A1)
Anatomy Link Frequency
body 3
FSHR (Homo sapiens)
CYP19A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 44 5.00 Very Low Very Low Very Low
agonist 34 5.00 Very Low Very Low Very Low
corticosteroid 8 5.00 Very Low Very Low Very Low
endometriosis 7 5.00 Very Low Very Low Very Low
dexamethasone 5 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 3 38 50.00 Quite Low
Breast Cancer 5 47.44 Quite Low
Endometriosis (extended) 13 5.00 Very Low Very Low Very Low
Polycystic Ovary Syndrome 12 5.00 Very Low Very Low Very Low
Obesity 11 5.00 Very Low Very Low Very Low
Ovarian Hyperstimulation Syndrome 11 5.00 Very Low Very Low Very Low
Spontaneous Abortion 9 5.00 Very Low Very Low Very Low
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
Edema 6 5.00 Very Low Very Low Very Low
Insulin Resistance 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As mentioned before, the rapid clearance of the aromatase inhibitors from the body due to their short half-life and the reversible nature of the aromatase enzyme inhibition as well as the rising levels of FSH, which induce the expression of the aromatase enzyme, all would not allow the clearance of any accumulating androgens by converting them to estrogen.
Gene_expression (levels) of FSH in body Positive_regulation (induce) of Gene_expression (expression) of aromatase enzyme in body
1) Confidence 0.16 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0 Pain Relevance 0

General Comments

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