INT18773

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Context Info
Confidence 0.80
First Reported 1982
Last Reported 2011
Negated 3
Speculated 2
Reported most in Abstract
Documents 117
Total Number 120
Disease Relevance 69.18
Pain Relevance 13.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ALB) small molecule metabolic process (ALB) enzyme binding (ALB)
DNA binding (ALB) protein complex (ALB) transmembrane transport (ALB)
Anatomy Link Frequency
urine 18
hepatocytes 6
plasma 4
kidney 4
blood 4
ALB (Homo sapiens)
Pain Link Frequency Relevance Heat
beta blocker 26 100.00 Very High Very High Very High
Chronic pancreatitis 4 100.00 Very High Very High Very High
Paracetamol 85 99.96 Very High Very High Very High
imagery 104 99.80 Very High Very High Very High
Bile 103 99.76 Very High Very High Very High
Inflammation 690 99.36 Very High Very High Very High
agonist 9 99.32 Very High Very High Very High
cva 60 99.22 Very High Very High Very High
lidocaine 5 99.20 Very High Very High Very High
peripheral neuropathy 43 98.28 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hypertension 731 100.00 Very High Very High Very High
Cancer 405 100.00 Very High Very High Very High
Pressure And Volume Under Development 298 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 177 100.00 Very High Very High Very High
Appetite Loss 49 100.00 Very High Very High Very High
Gallstones 44 100.00 Very High Very High Very High
Pancreatitis 16 100.00 Very High Very High Very High
Pleural Effusion 10 100.00 Very High Very High Very High
Bacterial Respiratory Disease 6 100.00 Very High Very High Very High
Sarcoma 15 99.98 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Flufenamic acid and ketoprofen released bilirubin from human serum albumin.
Localization (released) of serum albumin
1) Confidence 0.80 Published 1984 Journal Nippon Yakurigaku Zasshi Section Abstract Doc Link 6714852 Disease Relevance 0.09 Pain Relevance 0.09
After stepwise logistic regression, the variables that remained in the model explaining excreted albumin in the urine of adult males were presence of leukocytes in urine (OR?
Localization (excreted) of albumin in urine
2) Confidence 0.80 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2752803 Disease Relevance 0.40 Pain Relevance 0
Further, the production of albumin, lactate dehydrogenase release, lactate release, urea production, and glucose consumption were measured.
Localization (release) of albumin
3) Confidence 0.80 Published 2010 Journal Tissue Eng Part A Section Abstract Doc Link 19778170 Disease Relevance 0.32 Pain Relevance 1.11
Only isomeric conjugates of zomepirac glucuronide were released from zomepirac-albumin adduct by mild acid; no beta 1-isomer was detected.
Localization (released) of albumin
4) Confidence 0.80 Published 1990 Journal Drug Metab. Dispos. Section Abstract Doc Link 1981713 Disease Relevance 0 Pain Relevance 0
Hepatocytes in conventional cultures or embedded in coated alginate beads survived for about 10 days, secreted proteins, particularly albumin, and maintained several phase I and II enzymatic activities, namely ethoxyresorufin-O-deethylase, oxidation of nifedipine to pyridine, phenacetin deethylation to paracetamol, glucuroconjugation of paracetamol, and N-acetylation of procainamide.
Localization (secreted) of albumin in Hepatocytes associated with paracetamol
5) Confidence 0.79 Published 1997 Journal Transplantation Section Abstract Doc Link 9089217 Disease Relevance 0.07 Pain Relevance 0.19
Recently, Siemens released an improved Microalbumin assay (microALB_2) to measure urinary ALB on the automated, random access ADVIA 1650/1800, ADVIA 2400, and ADVIA 1200 Chemistry Systems.
Localization (released) of albumin
6) Confidence 0.78 Published 2009 Journal J. Clin. Lab. Anal. Section Abstract Doc Link 19774630 Disease Relevance 0.10 Pain Relevance 0
This process plays a major role in the stability and drug release of albumin nanoparticles.
Localization (release) of albumin
7) Confidence 0.76 Published 2010 Journal Int J Nanomedicine Section Body Doc Link PMC2948945 Disease Relevance 0 Pain Relevance 0
Figure 6 shows the in vitro release of cumulative amounts of noscapine from albumin nanoparticles as a function of time.
Localization (release) of albumin
8) Confidence 0.76 Published 2010 Journal Int J Nanomedicine Section Body Doc Link PMC2948945 Disease Relevance 0 Pain Relevance 0
High doses of AAP (2815 mg/l) diminished urea production by 15-30% and albumin secretion by 70-80%.
Localization (secretion) of albumin associated with paracetamol
9) Confidence 0.76 Published 2007 Journal ALTEX Section Abstract Doc Link 17361319 Disease Relevance 0.09 Pain Relevance 0.86
Use of a standardised and validated long-term human hepatocyte culture system for repetitive analyses of drugs: repeated administrations of acetaminophen reduces albumin and urea secretion.
Localization (secretion) of albumin in hepatocyte associated with paracetamol
10) Confidence 0.76 Published 2007 Journal ALTEX Section Title Doc Link 17361319 Disease Relevance 0.06 Pain Relevance 0.62
After removal of AAP, secretion of urea and albumin returned to control levels.
Localization (secretion) of albumin associated with paracetamol
11) Confidence 0.76 Published 2007 Journal ALTEX Section Abstract Doc Link 17361319 Disease Relevance 0.10 Pain Relevance 0.87
Serum concentrations of alpha1-acid glycoprotein increased, whereas total protein and albumin decreased.
Localization (decreased) of albumin
12) Confidence 0.75 Published 1999 Journal Eur. J. Clin. Pharmacol. Section Body Doc Link 10027658 Disease Relevance 0.06 Pain Relevance 0
The following variables were measured: transcapillary escape rate of albumin (initial disappearance of intravenously injected 125I-labelled human serum albumin), and urinary albumin excretion rate (radial immunodiffusion).
Localization (excretion) of albumin in radial
13) Confidence 0.75 Published 1985 Journal Diabetologia Section Abstract Doc Link 4085693 Disease Relevance 0.65 Pain Relevance 0.17
The following variables were measured: transcapillary escape rate of albumin (initial disappearance of intravenously injected 125I-labelled human serum albumin), and urinary albumin excretion rate (radial immunodiffusion).
Localization (excretion) of albumin in radial
14) Confidence 0.75 Published 1985 Journal Diabetologia Section Abstract Doc Link 4085693 Disease Relevance 0.67 Pain Relevance 0.17
0.05) prognostic factors for overall survival were age at diagnosis, FIGO stage, grade of tumor, histology (mixed mesodermal, clear cell and endometrioid versus serous papillary), the presence or absence of ascites, albumin, ALP, PS, and debulking of the tumor [81].
Localization (presence) of albumin associated with pressure and volume under development and cancer
15) Confidence 0.75 Published 2010 Journal Nutr J Section Body Doc Link PMC3019132 Disease Relevance 1.51 Pain Relevance 0
0.07) were identified more likely to be excreting elevated concentrations of albumin in urine (Table 4).
Localization (excreting) of albumin in urine
16) Confidence 0.75 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2752803 Disease Relevance 0.37 Pain Relevance 0
The effects of manidipine on urinary albumin excretion (UAE) have not been clearly demonstrated in clinical trials in this patient group.
Localization (excretion) of albumin
17) Confidence 0.73 Published 2001 Journal Drugs Section Abstract Doc Link 11693466 Disease Relevance 1.20 Pain Relevance 0.16
The effects of manidipine on urinary albumin excretion (UAE) have not been clearly demonstrated in clinical trials in this patient group.
Localization (excretion) of albumin
18) Confidence 0.73 Published 2001 Journal Drugs Section Abstract Doc Link 11693466 Disease Relevance 1.14 Pain Relevance 0.16
Slides were washed twice in PBS, incubated in 1% bovine serum albumin (BSA) for 5 min and then incubated for 1 h at room temperature with the following primary antibodies: anti-Cytokeratin 13 (Sigma) anti-Cytokeratin 18 (Sigma), anti-MUC5AC (gift from JP Aubert, Lille, France), anti-occludin (Zymed, San Francisco, CA), anti-zonula occludens (ZO-1) (Zymed), anti E-cadherin (R & D Systems, Minneapolis, MN), anti-IL-8 (Biosource International, Camarillo, CA), and Ki67 antigen (MIB-1 clone) (Immunotech, Marseille, France).
Localization (bovine) of serum albumin
19) Confidence 0.73 Published 2007 Journal Respir Res Section Body Doc Link PMC2214730 Disease Relevance 0 Pain Relevance 0
The patients were asked to bring two overnight (12 h) urine samples for determination of urinary albumin excretion by using an immunonephelometry method.
Localization (excretion) of albumin in urine
20) Confidence 0.73 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2621377 Disease Relevance 1.11 Pain Relevance 0.03

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