INT187880

Context Info Confidence 0.33 First Reported 2005 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 3 Disease Relevance 2.07 Pain Relevance 0.10

endosome (Abcg1) transport (Abcg1) Golgi apparatus (Abcg1) ATPase activity (Abcg1) plasma membrane (Abcg1) intracellular (Abcg1)

Anatomy Link Frequency liver 1 Abcg1 (Mus musculus)

Pain Link Frequency Relevance Heat fibrosis 1 79.28 ischemia 3 61.80 Bile 5 19.36 Kinase C 1 17.04 agonist 25 5.00 Inflammation 13 5.00 Bioavailability 8 5.00 aspirin 6 5.00 antagonist 4 5.00 Angina 3 5.00

Disease Link Frequency Relevance Heat Disorder Of Lipid Metabolism 300 98.80 Disease 24 82.08 Myocardial Infarction 24 80.76 Apoptosis 14 80.12 Cystic Fibrosis 1 79.84 Heart Disease 1 79.72 Death 12 79.60 Adrenoleukodystrophy 1 78.48 Atherosclerosis 56 73.84 Cancer 27 73.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore, resveratrol activates the cholesterol efflux genes ATP-binding cassette transporter 1 (ABCA1) and ATP-binding cassette transporter G1 (ABCG1), as well as transcription factors that influence the nuclear liver receptor-?

ABCG1 Binding (binding) of in liver

1) Confidence 0.33 Published 2008 Journal Clinical Interventions in Aging Section Body Doc Link PMC2546476 Disease Relevance 0.51 Pain Relevance 0.06

These receptors include ATP-binding cassette transporter A-1 (ABCA-1), ATP-binding cassette transporter G-1 (ABCG-1), and scavenger receptor class-B type-1 (SR-B1.

ABCG-1 Binding (binding) of

2) Confidence 0.08 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.70 Pain Relevance 0

Pgp is one of the membrane transporter superfamily having the ATP-binding cassette (ABC) with well-preserved homology of the site where ATP binds.

ATP-binding cassette Binding (binds) of

3) Confidence 0.02 Published 2005 Journal Cancer Cell Int Section Body Doc Link PMC1277830 Disease Relevance 0.86 Pain Relevance 0.04

General Comments

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