INT187898

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Pgp) carbohydrate metabolic process (Pgp) molecular_function (Pgp)
cellular_component (Pgp)
Pgp (Mus musculus)
Mir486 (Mus musculus)
Pain Link Frequency Relevance Heat
vincristine 1 21.40 Low Low
Bioavailability 8 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
antidepressant 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 3 70.80 Quite High
Drug Induced Neurotoxicity 1 65.44 Quite High
Toxicity 4 62.60 Quite High
Cancer 12 47.28 Quite Low
Leukemia 1 20.60 Low Low
Cv Unclassified Under Development 2 15.24 Low Low
Disease 6 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low
Adrenoleukodystrophy 1 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, the flavonoid, kaempferide, is bifunctional in that it would partially block the binding of the antiprogestin RU-486 in the cytoplasm domain of Pgp and block ATP binding [195] (Fig. 4).
Negative_regulation (block) of Pgp Binding (binding) of RU-486
1) Confidence 0.01 Published 2005 Journal Cancer Cell Int Section Body Doc Link PMC1277830 Disease Relevance 0.25 Pain Relevance 0

General Comments

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