INT18791

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Context Info
Confidence 0.49
First Reported 1989
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 2.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Crh, Penk) extracellular space (Crh) response to stress (Crh)
cytoplasm (Crh)
Anatomy Link Frequency
pallidum 1
Crh (Rattus norvegicus)
Penk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 19 100.00 Very High Very High Very High
Dynorphin 17 100.00 Very High Very High Very High
Opioid 5 92.12 High High
Dopamine 1 75.00 Quite High
antagonist 1 74.04 Quite High
Central nervous system 1 67.12 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the results of this study demonstrate that the action of CRF on Met-enkephalin as well as dynorphin release from the rat neostriatum is DA dependent.
CRF Regulation (dependent) of Met-enkephalin associated with dynorphin and enkephalin
1) Confidence 0.49 Published 1990 Journal Brain Res. Section Abstract Doc Link 1981853 Disease Relevance 0 Pain Relevance 0.78
Both the in vitro and in vivo studies thus demonstrate that CRF can exert potent effects on Met-enkephalin and dynorphin release within the neostriatum-pallidum of the rat and that such effects are mediated via receptors specific for CRF, probably located on both the cell bodies and terminals of these opioid-containing neurones.
CRF Regulation (effects) of Met-enkephalin in pallidum associated with dynorphin, enkephalin and opioid
2) Confidence 0.43 Published 1989 Journal Brain Res. Section Abstract Doc Link 2569903 Disease Relevance 0 Pain Relevance 1.38

General Comments

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